Benefits Of AstraZeneca’s COVID-19 Vaccine Outweigh Risks Despite ‘Possible Links’ Of Blood Clots, Says EU Regulator | News

April 8, 2021 0 Comments



European Medicines Agency’s scientific assessment underpins the safe and effective use of COVID-19 vaccines

Highlights
  • India is also using AstraZeneca’s COVID-19 vaccine called Covishield
  • Cases of blood clots after AstraZeneca’s vaccine shot have been reported
  • Reported combination of blood clots & low blood platelets is very rare: EMA

Brussels: The European Medicines Agency (EMA) on Wednesday (April 7) acknowledged a “possible link” between the AstraZeneca vaccine and “very rare cases of blood clots” but said the benefits of the vaccine, however, continue to outweigh the risks. According to a statement from the European medical body, the Pharmacovigilance Risk Assessment Committee (PRAC) “concluded today (Wednesday) that unusual blood clots with low blood platelets should be listed as very rare side effects of Vaxzevria (formerly COVID-19 Vaccine AstraZeneca).”

Also Read: Oxford-Astrazeneca Coronavirus Vaccine Is ‘Safe And Effective’: European Medicines Agency

In reaching its conclusion, the committee took into consideration all currently available evidence, including the advice from an ad hoc expert group, it added.

EMA said that it is reminding healthcare professionals and people receiving the vaccine to remain aware of the possibility of very rare cases of blood clots combined with low levels of blood platelets occurring within two weeks of vaccination. The body noted that so far, most of the cases reported have occurred in women under 60 years of age within 2 weeks of vaccination. Based on the currently available evidence, specific risk factors have not been confirmed.

The PRAC noted that the blood clots occurred in veins in the brain (cerebral venous sinus thrombosis, CVST) and the abdomen (splanchnic vein thrombosis) and in arteries, together with low levels of blood platelets and sometimes bleeding, it said.

The Committee carried out 62 cases of cerebral venous sinus thrombosis and 24 cases of splanchnic vein thrombosis reported in the EU drug safety database (EudraVigilance) as of 22 March 2021, 18 of which were fatal. The cases came “mainly from spontaneous reporting systems” of the EEA (European Economic Area) and the UK, where around 25 million people had received the vaccine, it added.

Also Read: Explainer: How Worried Should We Be About Reports Of Blood Clots And Astrazeneca’s Vaccine?

The reported combination of blood clots and low blood platelets is very rare, and the overall benefits of the vaccine in preventing COVID-19 outweigh the risks of side effects… EMA’s scientific assessment underpins the safe and effective use of COVID-19 vaccines. Use of the vaccine during vaccination campaigns at national level will also take into account the pandemic situation and vaccine availability in the individual Member State, the EMA said.

It also said that the PRAC stresses the importance of prompt specialist medical treatment. By recognising the signs of bloods clots and low blood platelets and treating them early, healthcare professionals can help those affected in their recovery and avoid complications.

Also Read: No COVID-19 Vaccine Shortage In Any Part Of Country, Carelessness Behind Surge In Cases: Union Health Minister

According to Sputnik, AstraZeneca said on Wednesday it was working to establish the causes of blood clots after vaccination against coronavirus with its drug, but emphasized that these were very rare cases. The company also said it was actively working with regulators to amend the description of the drug and is already working to understand the existing cases, epidemiology and possible mechanisms that explain these extremely rare cases. CNN also reported that the World Health Organization said it was “plausible” there was a link between the AstraZeneca vaccine and rare cases of blood clots. Having reviewed the latest information from the EU and UK regulators among others, the WHO said “a causal relationship between the vaccine and the occurrence of blood clots with low platelets is considered plausible but is not confirmed.”

Also Read: Indian Medical Association Urges PM Modi To Start Vaccination For All Above 18 Years, Suggests Limited Lockdown

WHO is carefully monitoring the rollout of all COVID-19 vaccines and will continue to work closely with countries to manage potential risks, and to use science and data to drive response and recommendations, it read in a statement.

It also said that “whilst concerning, the events under assessment are very rare, with low numbers reported among the almost 200 million individuals” who have received the vaccine worldwide.”

Also Read: Dynamic Strategy Prioritising COVID-19 Vaccines For Seniors, Essential Workers Offers Greatest Public Health Benefit: Study

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

NDTV – Dettol Banega Swasth India campaign is an extension of the five-year-old Banega Swachh India initiative helmed by Campaign Ambassador Amitabh Bachchan. It aims to spread awareness about critical health issues facing the country. In wake of the current COVID-19 pandemic, the need for WASH (WaterSanitation and Hygiene) is reaffirmed as handwashing is one of the ways to prevent Coronavirus infection and other diseases. The campaign highlights the importance of nutrition and healthcare for women and children to prevent maternal and child mortality, fight malnutrition, stunting, wasting, anaemia and disease prevention through vaccines. Importance of programmes like Public Distribution System (PDS), Mid-day Meal Scheme, POSHAN Abhiyan and the role of Aganwadis and ASHA workers are also covered. Only a Swachh or clean India where toilets are used and open defecation free (ODF) status achieved as part of the Swachh Bharat Abhiyan launched by Prime Minister Narendra Modi in 2014, can eradicate diseases like diahorrea and become a Swasth or healthy India. The campaign will continue to cover issues like air pollutionwaste managementplastic banmanual scavenging and sanitation workers and menstrual hygiene

World

13,53,52,898Cases

5,55,33,988Active

7,68,91,122Recovered

29,27,788Deaths

Coronavirus has spread to 192 countries. The total confirmed cases worldwide are 13,53,52,898 and 29,27,788 have died; 5,55,33,988 are active cases and 7,68,91,122 have recovered as on April 11, 2021 at 4:16 am.

India

1,33,58,805 152879Cases

11,08,087 61456Active

1,20,81,443 90584Recovered

1,69,275 839Deaths

In India, there are 1,33,58,805 confirmed cases including 1,69,275 deaths. The number of active cases is 11,08,087 and 1,20,81,443 have recovered as on April 11, 2021 at 2:30 am.

State & District Details

State Cases Active Recovered Deaths

DistrictCases

Mumbai45,478

Thane13,660

Pune9,920

Mumbai Suburban5,363

Aurangabad1,974

Nashik1,575

Raigad1,462

Palghar1,421

Solapur1,291

Jalgaon1,039

Akola757

Nagpur692

Kolhapur646

Satara629

Ratnagiri350

Amravati291

Dhule228

Hingoli208

Jalna201

Ahmednagar190

Nanded176

Yavatmal150

Sangli145

Latur139

Osmanabad125

Sindhudurg114

Buldhana88

Parbhani78

gondia69

Beed54

Nandurbar42

Gadchiroli42

Bhandara41

Chandrapur32

Washim13

Wardha11

33,43,951 55,411

5,38,160 2,097

27,48,153 53,005

57,638 309

DistrictCases

Kannur357

Kasaragod333

Palakkad224

Malappuram119

Kollam118

Thrissur106

Thiruvananthapuram104

Pathanamthitta98

Kozhikode90

Alappuzha76

Kottayam73

Ernakulam60

Idukki40

Wayanad36

11,60,204 6,194

40,095 3,593

11,15,342 2,584

4,767 17

DistrictCases

Udupi1,176

Kalaburagi669

Yadgir538

Bengaluru Urban529

Raichur369

Mandya346

Belagavi337

Bidar219

Hassan205

Davangere204

Vijayapura201

Dakshina Kannada179

Chikkaballapura149

Mysuru107

Bagalkote103

Uttara Kannada95

Shivamogga67

Dharwad61

Ballari60

Gadag45

Bengaluru Rural40

Tumakuru36

Kolar29

Haveri24

Chikkamagaluru19

Chitradurga14

Koppal5

Kodagu4

Ramanagara3

Chamarajanagara0

10,55,040 6,955

61,672 3,569

9,80,519 3,350

12,849 36

DistrictCases

Chennai23,324

Chengalpattu1,314

Thiruvallur774

Villupuram509

Kanchipuram503

Tiruvannamalai496

Cuddalore477

Ariyalur444

Tirunelveli433

Tuticorin333

Kallakurichi324

Madurai322

Salem258

Coimbatore188

Virudhunagar185

Dindigul175

Perambalur133

Ranipet133

Thanjavur130

Theni129

Tiruchirappalli119

Ramanathapuram119

Tiruppur116

Kanniyakumari110

Tenkasi103

Nagapattinam99

Karur88

Namakkal83

Erode75

Vellore71

Thiruvarur67

Pudukkottai53

Sivaganga46

Tirupathur45

Krishnagiri43

The Nilgiris17

Dharmapuri15

9,26,816 5,989

37,673 4,014

8,76,257 1,952

12,886 23

DistrictCases

Kurnool795

Krishna557

Guntur511

Anantapur428

East Godavari356

Chittoor319

Sri Potti Sriramulu Nell*296

Y.S.R.205

West Godavari199

Srikakulam183

Prakasam104

Visakhapatnam103

Vizianagaram23

9,21,906 3,309

18,666 2,244

8,95,949 1,053

7,291 12

DistrictCases

North West5,463

Central4,817

West4,768

New Delhi3,405

North3,059

East2,472

South East2,446

South West2,391

South2,329

North East1,914

Shahdara1,580

7,14,423 7,897

28,773 2,142

6,74,415 5,716

11,235 39

DistrictCases

Gautam Buddha Nagar1,119

Agra933

Ghaziabad794

Meerut504

Lucknow386

Saharanpur298

Kanpur Nagar286

Moradabad252

Varanasi243

Hapur225

Aligarh215

Basti214

Amethi206

Rampur203

Jaunpur194

Firozabad190

Barabanki168

Gorakhpur166

Bulandshahr166

Siddharth Nagar159

Ghazipur159

Bijnor157

Deoria143

Azamgarh138

Sant Kabeer Nagar132

Mathura129

Ayodhya120

Muzaffarnagar117

Sambhal116

Sultanpur97

Ambedkar Nagar92

Maharajganj85

Amroha80

Rae Bareli78

Bahraich73

Kheri72

Kannauj69

Baghpat68

Kushi Nagar67

Bhadohi60

Ballia60

Gonda59

Etah52

Hardoi49

Balrampur49

Mau48

Mainpuri46

Etawah46

Hathras43

Unnao42

Jalaun41

Jhansi41

Shamli40

Chandauli38

Auraiya37

Farrukhabad36

Sitapur32

Prayagraj30

Banda27

Shahjahanpur25

Shravasti23

Budaun23

Mirzapur22

Bareilly17

Kasganj16

Pratapgarh15

Pilibhit15

Sonbhadra10

Kaushambi6

Kanpur Dehat4

Chitrakoot4

Lalitpur3

Hamirpur3

Mahoba3

Fatehpur3

6,76,739 12,748

58,801 10,495

6,08,853 2,207

9,085 46

DistrictCases

Kolkata2,777

Howrah1,435

24 Paraganas North1,031

Hooghly604

24 Paraganas South281

Maldah235

Dinajpur Uttar216

Coochbehar210

Birbhum206

Medinipur West159

Medinipur East153

Nadia139

Purba Bardhaman130

Murshidabad125

Bankura116

Darjeeling97

Jalpaiguri88

Paschim Bardhaman70

Purulia66

Dinajpur Dakshin50

Alipurduar39

Kalimpong18

Jhargram9

6,10,498 4,043

21,366 2,763

5,78,742 1,268

10,390 12

DistrictCases

Bilaspur100

Korba100

Mungeli87

Baloda Bazar85

Jashpur77

Janjgir-Champa56

Mahasamund54

Rajnandgaon52

Kabirdham52

Raigarh47

Raipur46

Balod41

Korea39

Durg31

Bemetara21

Kanker19

Balrampur17

Surguja14

Gariyaband10

Surajpur9

Dhamtari6

Bijapur2

Bastar2

Dantewada0

Kondagaon0

Narayanpur0

Sukma0

4,32,776 14,098

85,860 8,992

3,42,139 4,983

4,777 123

DistrictCases

Jaipur2,177

Jodhpur1,748

Udaipur724

Bharatpur563

Kota503

Nagaur500

Ajmer379

Dungarpur374

Pali352

Jhalawar329

Bhilwara250

Sikar231

Chittorgarh188

Tonk171

Jalore164

Rajsamand140

Sirohi130

Bikaner112

Banswara91

Alwar90

Churu81

Jhunjhunu64

Dausa61

Dholpur60

Baran59

Jaisalmer53

Barmer34

Hanumangarh31

SawaiMadhopur26

Karauli17

Pratapgarh14

Ganganagar8

Bundi5

3,58,688 4,401

27,906 3,821

3,27,866 562

2,916 18

DistrictCases

Ganjam581

Jajapur322

Khordha238

Baleshwar190

Kendrapara164

Cuttack155

Bhadrak137

Balangir129

Puri103

Sundargarh102

Jagatsinghapur91

Nayagarh86

Mayurbhanj73

Nuapada69

Gajapati61

Dhenkanal36

Boudh34

Kendujhar34

Deogarh33

Kalahandi33

Sonepur29

Kandhamal28

Anugul26

Malkangiri20

Bargarh16

Koraput16

Sambalpur16

Jharsuguda8

Nabarangpur2

Rayagada2

3,48,182 1,374

6,653 969

3,39,603 403

1,926 2

DistrictCases

Ahmadabad17,125

Surat2,311

Vadodara1,555

Gandhinagar410

Mahesana159

Banas Kantha147

Bhavnagar146

Rajkot135

Arvalli134

Mahisagar125

Anand107

PanchMahals107

Patan105

SabarKantha101

Kachchh99

Kheda98

Jamnagar63

Bharuch56

Botad55

Surendranagar55

Valsad47

GirSomnath45

Dohad43

Chhotaudepur37

Naysari35

Junagadh31

Narmada25

DevbhumiDwarka22

Amreli16

Porbandar11

Tapi6

Dang5

Morbi4

3,42,026 5,011

25,129 2,437

3,12,151 2,525

4,746 49

DistrictCases

Indore3,839

Bhopal1,880

Ujjain799

Burhanpur351

Neemuch319

Jabalpur276

East Nimar266

Sagar228

Gwalior211

Khargone196

Dewas140

Dhar132

Mandsaur112

Morena109

Bhind87

Raisen71

Barwani60

Ratlam51

Rewa39

Shajapur39

Hoshangabad37

Vidisha37

Chhatarpur35

Betul35

Rajgarh31

Dindori29

Sheopur26

Damoh26

Satna24

Anuppur22

Panna20

Tikamgarh18

Sidhi17

Narsinghpur17

Chhindwara16

Agar Malwa15

Mandla15

Shivpuri15

Jhabua14

Shandol14

Singrauli13

Ashoknagar13

Datia12

Sehore12

Umaria10

Balaghat9

Guna8

Harda4

Alirajpur3

Katni3

Seoni2

Niwari0

3,32,206 4,986

32,707 2,221

2,95,339 2,741

4,160 24

DistrictCases

Hyderabad2,475

Ranga Reddy183

Suryapet87

Jagitial77

Nizamabad76

MedchalMalkajgiri75

Mancherial43

YadadriBhuvanagiri40

Jogulamba Gadwal40

Vikarabad40

Nalgonda33

Warangal Urban32

Mahabubnagar30

Sangareddy26

Khammam26

Adilabad22

Nirmal21

Karimnagar17

RajannaSircilla16

Medak11

Kamareddy11

Mahabubabad10

Jayashankar Bhupalapally9

Nagarkurnool8

Kumuram Bheem Asifabad8

Jangoan8

Siddipet7

Peddapalli5

Bhadradri Kothagudem5

Warangal Rural4

Mulugu3

Narayanpet3

Wanaparthy1

3,27,278 3,187

20,184 2,393

3,05,335 787

1,759 7

DistrictCases

Gurugram2,950

Faridabad867

Sonipat404

Rohtak145

Palwal120

Jhajjar114

Karnal104

Hisar98

Ambala93

Panipat78

Nuh68

Bhiwani60

Rewari56

Kurukshetra55

Sirsa50

Kaithal48

Mahendragarh47

CharkiDadri43

Panchkula39

Fatehabad38

Jind38

Yamunanagar19

3,13,441 2,937

19,453 1,311

2,90,736 1,615

3,252 11

DistrictCases

Patna279

Bhagalpur266

Rohtas256

Khagaria253

Begusarai243

Madhubani199

Munger188

Jehanabad178

Katihar175

Darbhanga143

Samastipur139

Siwan139

PurbiChamparan138

Purnia135

Banka134

Buxar134

Nalanda123

Gopalganj123

Nawada122

Sheikhpura118

Gaya115

Kaimur (bhabua)105

Bhojpur103

Saran101

Muzaffarpur96

Saharsa88

Supaul87

Vaishali87

Madhepura82

Kishanganj75

Aurangabad75

Sitamarhi73

Lakhisarai72

Araria68

Pashchim Champaran57

Arwal52

Jamui47

Sheohar20

2,79,473 3,469

11,999 2,641

2,65,870 822

1,604 6

DistrictCases

Amritsar485

Jalandhar297

Ludhiana293

Tarn Taran163

Gurdaspur154

Hoshiarpur140

S.A.S Nagar137

Patiala132

Sangrur107

Shahid Bhagat Singh Nagar (Nawanshahr)99

Pathankot86

Rupnagar (Ropar)74

Faridkot74

Sri Muktsar Sahib71

Moga65

Bathinda60

Fatehgarh Sahib57

Fazilka53

Firozepur50

Kapurthala44

Mansa31

Barnala25

2,69,733 3,239

28,015 796

2,34,270 2,385

7,448 58

DistrictCases

Kamrup Metro276

Golaghat203

Nagaon143

Hojai89

Dima Hasao86

Karimganj85

Tinsukia84

Cachar80

Dibrugarh61

Hailakandi57

Lakhimpur57

Marigaon50

Dhemaji47

Kamrup42

Kokrajhar37

Dhubri30

Charaideo29

Barpeta28

Udalguri28

Sonitpur27

Jorhat24

Nalbari23

Darrang20

Sivasagar20

Goalpara19

Biswanath16

Baksa14

KarbiAnglong13

Bongaigaon12

Chirang6

West KarbiAnglong5

South SalmaraMancachar4

Majuli2

2,19,958 405

2,934 324

2,15,907 79

1,117 2

DistrictCases

Anantnag395

Srinagar300

Kulgam295

Baramulla271

Shopian255

Kupwara231

Bandipora175

Udhampur155

Ramban151

Jammu138

Budgam110

Pulwama108

Kathua53

Rajouri39

Ganderbal37

Poonch35

Doda27

Reasi26

Samba25

Kishtwar10

Mirpur0

Muzaffarabad0

1,37,475 1,005

6,755 640

1,28,691 359

2,029 6

DistrictCases

East Singhbum170

Ranchi148

Hazaribagh110

Garhwa80

Ramgarh75

Koderma58

Simdega48

Dhanbad32

Gumla28

Palamu27

West Singhbhum21

SaraikelaKharsawan20

Giridih19

Bokaro16

Latehar14

Khunti10

Lohardaga8

Deoghar5

Dumka5

Pakur4

Jamtara2

Godda2

Chatra1

Sahebganj0

1,37,088 2,373

12,293 1,689

1,23,603 667

1,192 17

DistrictCases

Dehradun370

Nainital323

Tehri Garhwal110

Haridwar94

Udam Singh Nagar83

Almora71

Champawat45

Pithoragarh43

Chamoli36

PauriGarhwal36

Bageshwar31

Rudraprayag30

Uttar Kashi24

1,07,479 1,233

6,241 857

99,486 373

1,752 3

DistrictCases

Hamirpur117

Kangra105

Una41

Solan32

Chamba29

Bilaspur21

Mandi21

Sirmaur11

Shimla10

Kullu4

Kinnaur2

Lahaul And Spiti0

69,114 941

5,223 564

62,776 365

1,115 12

DistrictCases

South Goa69

North Goa57

61,779 540

3,969 372

56,964 167

846 1

DistrictCases

Pondicherry111

Mahe4

Karaikal2

Yanam0

43,737 272

2,218 134

40,830 136

689 2

DistrictCases

Dhalai196

Sepahijala174

Gomati74

South Tripura53

Unakoti49

West Tripura45

Khowai24

North Tripura14

33,733 48

236 48

33,104

393

DistrictCases

Chandigarh313

30,341 398

3,265 52

26,680 343

396 3

DistrictCases

Churachandpur32

Kangpokpi26

Imphal West21

Thoubal18

Imphal East10

Tengnoupal9

Bishnupur7

Senapati6

Chandel5

Kamjong5

Ukhrul4

Jiribam3

Pherzawl3

Kakching2

Tamenglong2

Noney1

29,486 11

101 10

29,010 1

375

DistrictCases

Changlang31

Papum Pare8

Lohit3

Namsai2

West Siang1

East Siang1

Upper Siang1

Tawang1

PakkeKessang1

West Kameng0

Upper Subansiri0

Tirap0

Siang0

Shi Yomi0

Anjaw0

Lower Subansiri0

Lower Dibang Valley0

Longding0

Leparada0

KurungKumey0

KraDaadi0

Kamle0

East Kameng0

Dibang Valley0

Lower Siang0

16,878 3

32 2

16,790 1

56

DistrictCases

East Khasi Hills22

West Garo Hills5

South West Garo Hills4

North Garo Hills1

West Jaintia Hills1

West Khasi Hills1

East Garo Hills0

East Jaintia Hills0

Ribhoi0

South Garo Hills0

South West Khasi Hills0

14,246 39

202 35

13,893 4

151

DistrictCases

Dimapur20

Mon8

Kohima7

Kiphire3

Tuensang3

Peren2

Phek1

Longleng0

Mokokchung0

Wokha0

Zunheboto0

12,400 12

156 10

12,152 2

92

DistrictCases

Kargil77

LehLadakh43

10,765 146

611 54

10,023 91

131 1

DistrictCases

East District3

South District3

North District0

West District0

6,351 22

116 15

6,099 7

136

DistrictCases

South Andamans33

Nicobars1

North And Middle Andaman1

5,175 14

75 4

5,038 10

62

DistrictCases

Kolasib11

Aizawl10

Mamit8

Lawngtlai2

Lunglei2

Saitual1

Champhai0

Hnahthial0

Khawzawl0

Saiha0

Serchhip0

4,612 29

143 28

4,458 1

11

DistrictCases

Dadra And Nagar Haveli20

4,014 130

345 115

3,667 15

2

DistrictCases

Lakshadweep District0

794 10

60 5

733 5

1





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